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KMID : 0545120170270101773
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Journal of Microbiology and Biotechnology
2017 Volume.27 No. 10 p.1773 ~ p.1777
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Oleaginous Yeast Rhodosporidium toruloides as a Tool for Rapid Evaluation of Anti-Obesity Candidates: Inhibitory Effect of Persimmon Leaf Fermentate on Lipid Accumulation
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Lee Nam-Keun
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Abstract
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The aim of this study was to examine the efficiency of Rhodosporidium toruloides as a new tool to evaluate the triglyceride (TG) reduction effects of anti-obesity candidate materials. Unfermented and fermented persimmon leaf hot water extracts (UFPLE and FPLE) were used as anti-obesity agents. The content of TG in R. toruloides treated with FPLE was less than those with UFPLE by about 11% (p < 0.05) relative to the control (R. toruloides incubated in YPD medium without the agents). Fat reduction in 3T3-L1 cells achieved by FPLE was about 13% higher than that achieved by UFPLE.
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KEYWORD
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Persimmon leaf, fermentation, lactic acid bacteria, triglyceride, lipid accumulation, Rhodosporidium toruloides
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